REUTERS: Wall Street's main indexes tumbled at the open on Friday after President Donald Trump tested positive for COVID-19 weeks before the election, with an elusive fiscal stimulus and a slowdown in the domestic economic recovery also denting sentiment.
All 11 major S&P sectors were down, with energy sliding 1.5per cent on the back of a more than 3per cent drop in oil prices.
Utilities , healthcare and consumer staples were among the smallest decliners in early trading.
Trump's tweet that he and first lady Melania had contracted the disease rankled global financial markets and sent investors scurrying to the perceived safety of the dollar, yen and gold.
Analysts said the news could hurt Trump's campaigning ability and jack up market volatility at a time when investors were already skittish after a chaotic presidential debate heightened fears of a messy transfer of power.
"It's one more insecurity heading into a tight, contentious election," said Oliver Pursche, president of Bronson Meadows Capital Management in Fairfield, Connecticut.
"And given that Trump does not adhere to conventional norms and rules, who knows what he'll do in terms of postponing the elections."
A senior White House official said the president is "not incapacitated" and will work from his residence.
After Trump said he had the coronavirus, online gambling site Betfair suspended betting on the outcome of the election. Betfair's odds had previously shown Democratic challenger Joe Biden's probability of winning at 60per cent on Wednesday.
At 9:37 a.m. ET, the Dow Jones Industrial Average was down 0.99per cent, the S&P 500 was down 1.25per cent and the Nasdaq Composite was down 1.68per cent.
The risk-off mood sparked a broad-based decline, with banks tracking Treasury yields lower and tech mega-caps, which generally tend to outperform at a time of economic uncertainty, slumping between 1.6per cent and 2.3per cent.
Tesla Inc slipped 4.1per cent even as it reported record vehicle deliveries in the third quarter.
Trading on Wall Street turned choppy last month, with the S&P 500 snapping a five-month gaining streak, as economic data indicated a long road to pre-pandemic levels and Congress deliberated over the next round of fiscal stimulus.
With a bipartisan deal eluding House Speaker Nancy Pelosi and the White House, the U.S. House of Representatives on Thursday approved a US$2.2 trillion Democratic plan on fiscal aid, but objections from top Republicans are likely to doom the plan in the Senate.
Airlines including United Airlines Holding Inc , Delta Air Lines Inc , JetBlue Airways Corp and American Airlines Group Inc fell more than 2per cent.
Meanwhile, data showed U.S. job growth slowed more than expected in September as the recovery from the COVID-19 slump shifts into lower gear, although the unemployment rate fell to 7.9per cent from 8.4per cent in August.
"My initial reaction was, 'ouch!' I don't think it's going to do anything for the market; it's not positive enough," said Patrick Leary, chief market strategist at Incapital in Minneapolis.
The CBOE volatility index , known as Wall Street's fear gauge, shot up to a one-week high.
Declining issues outnumbered advancers 9.77-to-1 on the NYSE and 8.50-to-1 on the Nasdaq.
The S&P index recorded no new 52-week high and one new low, while the Nasdaq recorded three new highs and 21 new lows.
(Reporting by Sagarika Jaisinghani and Devik Jain in Bengaluru; Additional reporting by Herbert Lash and Stephen Culp in New York; Editing by Shounak Dasgupta and Arun Koyyur)