'Prediabetes' common in US teens, young adults

'Prediabetes' common in US teens, young adults

(Reuters Health) - About one in five teens and one in four young adults in the U.S. have slightly elevated blood sugar, sometimes known as "prediabetes," that can lead to full-blown diabetes, a study suggests.

For the study, researchers examined data on blood sugar levels for 5,786 people ages 12 to 34 who hadn't been diagnosed with diabetes. Overall, 18per cent of the younger people in the study, ranging in age from 12 to 18 years old, had "prediabetes," as did 24per cent of the adults 19 to 34 years old.

"Prediabetes is highly prevalent in U.S. adolescents and young adults, especially in male individuals and in people with obesity," lead study author Linda Andes of the U.S. Centers for Disease Control and Prevention in Atlanta and colleagues write in JAMA Pediatrics.

These teens and young adults with prediabetes are at increased risk not only for developing type 2 diabetes - the common form of the disease associated with obesity and aging - but also cardiovascular problems that can lead to heart attacks and strokes, the study team writes.

"These findings together with the observed increase in the prevalence of type 2 diabetes in U.S. adolescents and in diabetes-related complications in young adults highlight the need for ... prevention efforts tailored to the young segment of the U.S. population," the study team notes.

Average blood sugar levels over the course of about three months can be estimated by measuring a form of hemoglobin that binds to glucose in blood, known as A1c. Hemoglobin A1c levels of 6.5per cent or above signal diabetes.

Levels between 5.7per cent and 6.4per cent are considered elevated, though not yet diabetic, while 5.7per cent or less is considered normal.

Overall, 5.3per cent of teens and 8per cent of young adults in the study had levels in this "prediabetic" range, the study found.

To get a more complete picture of how many young people might be at risk for developing full-blown diabetes, researchers also looked at other things including so-called insulin resistance, or the body's failure to respond normally to the hormone insulin. Diabetes can develop when the body can't properly use insulin to convert blood sugar into energy.

They also looked at what's known as impaired fasting glucose, when blood sugar levels are above a normal range but not quite high enough to formally diagnose diabetes.

Both teens and young adults in the study who appeared to have prediabetes had higher cholesterol and blood pressure and more fat stored around their midsections than individuals without prediabetes.

Among teens in the study, about 23per cent of males had prediabetes, compared with 13per cent of females. Differences persisted among young adults: 29per cent of males and 19per cent of females had prediabetes.

And, less than 16per cent of white teens had prediabetes, compared with more than 22per cent of black and Hispanic adolescents. This difference also carried through to early adulthood: about 21per cent of white people had prediabetes compared with 27per cent of black individuals and 29per cent of Hispanic young adults.

People with obesity were also most likely to have prediabetes: 26per cent of teens and 37per cent of young adults with obesity had this condition.

The study wasn't a controlled experiment designed to prove whether or how markers of prediabetes might directly lead to diabetes in teens or young adults.

One limitation of the study is that researchers only had data to assess prediabetes at a single point in time, the study authors note.

SOURCE: http://bit.ly/37YCWKo JAMA Pediatrics, online December 2, 2019.

Source: Reuters

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