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How Moderna’s COVID-19 vaccine will be rolled out in the US

How Moderna’s COVID-19 vaccine will be rolled out in the US

A small shopping basket filled with vials labeled "COVID-19 - Coronavirus Vaccine" and medical sryinges are placed on a Moderna logo in this illustration taken November 29, 2020. Picture taken November 29, 2020. REUTERS/Dado Ruvic/Ilustration

DETROIT: US distribution of a second COVID-19 vaccine, from Moderna, is ready to start shipping to more than 3,800 sites this weekend, vastly widening the rollout begun last week with Pfizer, the drug company and distributor McKesson said on Saturday (Dec 19).

The Food and Drug Administration on Friday approved an emergency-use authorisation for the Moderna vaccine, the second after Pfizer and its German partner BioNTech.

Workers in pharmaceutical services provider Catalent's facility in Bloomington, Indiana, will fill and package vials with Moderna vaccine and hand off to McKesson, which will ship doses from facilities including Louisville, Kentucky and Memphis, Tennessee. Those locations are close to air hubs for United Parcel Service and FedEx.

The start of delivery for the Moderna vaccine will significantly widen availability of COVID-19 vaccines as US deaths related to the respiratory virus set records.

“This is now a footrace between the vaccine and COVID,” New York Governor Andrew Cuomo said on Friday at a briefing on the virus.

He said the state expects to receive 346,000 doses of the Moderna vaccine next week. Those will go to 292 medical facilities across the state.

READ: US authorises Moderna as second COVID-19 vaccine

Pfizer organised its own distribution system but the US government's Operation Warp Speed, led by an Army general, is in charge for Moderna. The Moderna delivery system will have some of the same players as Pfizer's but will differ in key ways.

Transportation companies UPS and FedEx are giving priority to vaccines on planes and trucks that are moving holiday gifts and other cargo. Their drivers will handle the bulk of the last-mile Moderna vaccine deliveries. They are going directly to vaccination sites, unlike Pfizer's which was sent to large hubs and redistributed.

Moderna's vaccine is available in quantities as small as 100 doses and can be stored for 30 days in standard-temperature refrigerators, while the inoculations from Pfizer come in boxes of 975 doses, must be shipped and stored at -70 degrees Celsius, and can be held for only 5 days at standard refrigerator temperatures.

The low-temperature logistics chain for two Covid-19 vaccines AFP/Paz PIZARRO

Texas and Arkansas officials told Reuters they expect Moderna to be the primary vaccine for rural areas, which often lack the ultra-cold storage equipment to store full trays of Pfizer's vials. Once the plastic on a Pfizer 975-dose tray is opened, recipients have 120 hours to use the vaccine.

US Army General Gus Perna, chief operating officer of the government's Operation Warp Speed program, said on a Monday press call that doses of Moderna's vaccine will be shipped to 3,825 US sites.

Initial doses were given to health professionals.

Programmes by pharmacies Walgreens and CVS to distribute the Pifzer vaccine to long-term care facilities are expected to start on Monday, Gareth Rhodes, a member of the New York governor’s COVID-19 task force said.

And a Centers for Disease Control and Prevention advisory panel on Sunday will consider what groups should get vaccinated next.

READ: Pfizer-BioNTech, Moderna and Sinovac: A look at three key COVID-19 vaccines

"The logistics will be easier with the Moderna vaccine," said Jesse Breidenbach, senior executive director of pharmacy for Sanford Health, which operates almost four dozen hospitals in South Dakota, North Dakota, Minnesota and Iowa.

"Thirty days in the refrigerator will make it a bit easier to deal with," Breidenbach said.

Still, doses of vaccine must travel with security guards, including US Marshals, and will be stored in locked refrigerators.

US officials have said they expect to have 40 million doses of the Pfizer-BioNTech and Moderna vaccines by the end of the year - enough to inoculate 20 million people.

Both vaccines were about 95 per cent effective at preventing illness in pivotal clinical trials with no serious safety issues.

Separately, US officials said Pfizer is preparing to distribute 2 million additional doses of its vaccine to locations around the US next week, with preparations for shipping beginning over the weekend.

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Source: Reuters/jt


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